Thierry Horner Selected Research

Nausea

1/2022	Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein in testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study.
4/2020	Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.

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Thierry Horner Research Topics

Disease

3	Thrombocytopenia (Thrombopenia) 01/2023 - 04/2020
3	Neoplasms (Cancer) 01/2022 - 12/2019
2	Breast Neoplasms (Breast Cancer) 11/2023 - 01/2022
2	Carcinoma (Carcinomatosis) 01/2022 - 04/2020
2	Nausea 01/2022 - 04/2020
1	Disease Progression 11/2023
1	Multiple Myeloma 01/2023
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2023
1	Hematologic Neoplasms (Hematological Malignancy) 01/2023
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2023
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2023
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2022
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022
1	Triple Negative Breast Neoplasms 01/2022
1	Anemia 04/2020
1	Diarrhea 04/2020
1	Fatigue 04/2020
1	Dysgeusia (Parageusia) 04/2020
1	Vomiting 04/2020

Drug/Important Bio-Agent (IBA)

4	molibresibIBA 11/2023 - 04/2020
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2022 - 04/2020
1	ErbB Receptors (EGF Receptor)IBA 01/2024
1	Cyclin-Dependent Kinase 4IBA 01/2024
1	Hormones (Hormone)IBA 11/2023
1	Fulvestrant (Faslodex)FDA Link 11/2023
1	Aromatase InhibitorsIBA 11/2023
1	Estrogen ReceptorsIBA 01/2022
1	GSK-2816126IBA 12/2019
1	Enhancer of Zeste Homolog 2 ProteinIBA 12/2019

Therapy/Procedure

1	Therapeutics 11/2023
1	Castration 01/2022
1	Drug Tapering 01/2022